230971-72-9Losartan Potassium Impurity M
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| Catalogue No.: | VL214007 |
|---|---|
| CAS No.: | 230971-72-9 |
| Mol. Formula: | C44H44Cl2N12O |
| Mol. Weight: | 827.81 g/mol |
Additional information on CAS 230971-72-9
Parent drug
LosartanIUPAC Name
[2-butyl-1-[[2′-[2-[[2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2Htetrazol-5-yl]biphenyl-4-yl]methyl]-4-chloro-1H-imidazol- 5-yl]methanolPharmacopoeial Synonyms
Losartan 2H-Dimer; Losartan Related Compound EOther Synonyms
Losartan N2-Dimer; N2-Losartanyl LosartanSmile
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CN5N=C(N=N5)C6=CC=CC=C6C7=CC=C(C=C7)CN8C(=NC(=C8CO)Cl)CCCC)ClInChI
InChI=1S/C44H44Cl2N12O/c1-3-5-15-39-47-41(45)37(56(39)25-29-17-21-31(22-18-29)33-11-7-9-13-35(33)43-49-53-54-50-43)27-58-52-44(51-55-58)36-14-10-8-12-34(36)32-23-19-30(20-24-32)26-57-38(28-59)42(46)48-40(57)16-6-4-2/h7-14,17-24,59H,3-6,15-16,25-28H2,1-2H3,(H,49,50,53,54)Characterization Data (Included)
HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).Additional Characterization Data
QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.Description
Losartan EP Impurity M also known as Losartan 2H-Dimer; Losartan Related Compound E , in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Losartan.
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