N-Nitroso Azithromycin EP Impurity M
It is one of impurity present in azithromycin, Azithromycin is a broad-spectrum macrolide antibiotic with bacteriostatic activity against many Gram-positive and Gram-negative bacteria including Bordetella pertussis and Legionella species. which is used for the treatment of respiratory, enteric, and genitourinary infections and may be used in preference to other macrolides for some sexually transmitted and enteric infections.
Additional information on N-nitroso azithromycin EP impurity M
N-((2S, 3R, 4S, 6R)-2-(((2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-2-ethyl-3, 4, 10-trihydroxy-13-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3, 5, 6, 8, 10, 12, 14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl)oxy)-3-hydroxy-6-methyltetrahydro-2H-pyran-4-yl)-N-nitrosoformamide
McMullan, B. K., & Mostaghim, M. (2015). Prescribing azithromycin. Australian Prescriber, 38(3), 87–89. https://doi.org/10.18773/austprescr.2015.030
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