Stock Locations

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Stock subject to availability.

Documentation

Download MSDS

Download Sample COA

Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

N-Nitroso of N-Demethyl Erythromycin A

● In Stock

Catalogue No.:	VE007865
CAS No.:	N/A
Mol. Formula:	C36H64N2O14
Mol. Weight:	748.90 g/mol

Request a quote

Add to RFQ list

Additional information on N-Nitroso of N-Demethyl Erythromycin A

Parent drug

Azithromycin / Erythromycin

IUPAC Name

N-((2S, 3S, 4S, 6S)-2-(((3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-14-ethyl-7, 12, 13-trihydroxy-4-(((4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3, 5, 7, 9, 11, 13-hexamethyl-2, 10-dioxooxacyclotetradecan-6-yl)oxy)-3-hydroxy-6-methyltetrahydro-2H-pyran-4-yl)-N-methylnitrous amide

Pharmacopoeial Synonyms

N/A

Other Synonyms

N/A

Smiles

O=NN([C@@H]1[C@H](O)[C@H](O[C@@H]([C@](C)(O)C[C@H]2C)[C@@H](C)[C@H](OC3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C2=O)=O)O[C@@H](C)C1)C

InChI

InChI=1S/C36H64N2O14/c1-13-24-36(10,45)29(41)19(4)26(39)17(2)15-34(8,44)31(52-33-27(40)23(38(11)37-46)14-18(3)48-33)20(5)28(21(6)32(43)50-24)51-25-16-35(9,47-12)30(42)22(7)49-25/h17-25,27-31,33,40-42,44-45H,13-16H2,1-12H3/t17-,18+,19+,20+,21-,22+,23+,24-,25?,27+,28+,29-,30+,31-,33+,34-,35-,36-/m1/s1

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Description

N-Nitroso of N-Demethyl Erythromycin A (Azithromycin) is an N-nitroso derivative of the secondary amine present in Azithromycin | which is a highly characterized reference material that meets stringent regulatory standards set for nitrosamine compounds | including those set by USP | EMA | JP | and BP. This nitroso standard is essential for a variety of applications | such as analytical method development | method validation (AMV) | and Quality Control (QC) | particularly in the context of Azithromycin production. It is suitable for use in both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA). This nitrosamine standard helps establish detection limits | quantify impurity levels | and ensure trace nitroso impurities in pharmaceutical products remain within FDA and EMA safety limits.