1246819-22-6: N-Nitroso Desloratadine

1246819-22-6: N-Nitroso Desloratadine

It is biotransformation of Desloratadine which is an orally potent peripheral histamine H1-receptor inhibitor and doesn’t have any sedative properties and is also evaluated for the treatment of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR) and chronic idiopathic urticaria (CIU).

Additional information on CAS 1246819-22-6

Catalogue No.

VE007389
CAS No.

1246819-22-6
Molecular Formula

C19H18ClN3O
Molecular Weight

339.82 g/mol
Parent drug

Desloratadine
IUPAC Name

8-Chloro-6, 11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine
Synonyms

N/A
References

Brambilla, Giovanni, et al. “Genotoxicity and Carcinogenicity Studies of Antihistamines.” Archives of Toxicology, vol. 85, no. 10, Feb. 2011, pp. 1173–87, https://doi.org/10.1007/s00204-011-0659-4.?Murdoch, David, et al. “Desloratadine.” Drugs, vol. 63, no. 19, 2003, pp. 2051–77, https://doi.org/10.2165/00003495-200363190-00010.?
Status

In-stock

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1246819-22-6: N-Nitroso Desloratadine

1246819-22-6: N-Nitroso Desloratadine
Catalogue No.

VE007389
CAS No.

1246819-22-6
Molecular Formula

C19H18ClN3O
Molecular Weight

339.82 g/mol
Parent drug

Desloratadine
IUPAC Name

8-Chloro-6, 11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine
Synonyms

N/A
Smile
References

Brambilla, Giovanni, et al. “Genotoxicity and Carcinogenicity Studies of Antihistamines.” Archives of Toxicology, vol. 85, no. 10, Feb. 2011, pp. 1173–87, https://doi.org/10.1007/s00204-011-0659-4.?Murdoch, David, et al. “Desloratadine.” Drugs, vol. 63, no. 19, 2003, pp. 2051–77, https://doi.org/10.2165/00003495-200363190-00010.?
Status

In-stock
ListName

N-Nitroso Desloratadine
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