2892260-32-9: N-Nitroso Sitagliptin Impurity
It is an impurity present in sitagliptin. It is a dipeptidyl-peptidase inhibitor (DPP-4 inhibitor), which is used for the therapy of type 2 diabetes, sitagliptin is effective in lowering HbA1c, which stimulates insulin secretion when hyperglycemia is present and inhibits glucagon secretion.
Additional information on N-Nitroso Sitagliptin Impurity
7-nitroso-3-(trifluoromethyl)-5, 6, 7, 8-tetrahydro-[1, 2, 4]triazolo[4, 3-a]pyrazine
Sitagliptin Impurity 100; 7-nitroso-3-(trifluoromethyl)-5,6,7,8- VE009183 N/A 100,00 720,00 tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Gallwitz, B. (2007). Review of sitagliptin phosphate: a novel treatment for type 2 diabetes. Vascular Health and Risk Management, 3(2), 203–210. https://doi.org/10.2147/vhrm.2007.3.2.203
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