936630-57-8: Sitagliptin Acid

Sitagliptin Acid / Sitagliptin FP Impurity E / Sitagliptin EP Impurity E (free base)(CAS No: 936630-57-8) or (3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, is inhibiting DPP-4 inactivation of the incretin hormones glucagon to improved glycaemic control.

Additional information

Additional information on CAS 936630-57-8

Catalogue No.

VE006432

CAS No.

936630-57-8

Molecular Formula

C10H10F3NO2

Molecular Weight

233.19 g/mol

Parent drug

Sitagliptin

IUPAC Name

(3R)-3-Amino-4-(2, 4, 5-trifluorophenyl)butanoic acid

Synonyms

Sitagliptin FP Impurity E / Sitagliptin EP Impurity E (free base)

References

By Katherine A Lyseng-Williamson Container: Drugs Year: 2007 Volume: 67 Issue: 4 DOI: 10.2165/00003495-200767040-00007 URL: https://link.springer.com/article/10.2165/00003495-200767040-00007

Status

In-stock

Other products related to sitagliptin

Name of Impurity	Catalogue No.
Methyl 3-oxo-4-(2, 4, 5-trifluorophenyl)butanoate	VE009010	View CAS 769195-26-8
Methyl 4-(2, 4-difluorophenyl)-3-oxobutanoate	VE009113	View
Methyl 4-(2, 5-difluorophenyl)-3-oxobutanoate	VE009112	View
Methyl 4-(3, 4-difluorophenyl)-3-oxobutanoate	VE009002	View
N, N'-(Ethane-1, 2-diyl)bis(3-amino-4-(2, 4, 5-trifluorophenyl)butanamide) Dihydrochloride	VE008996	View
N-butanoyl Sitagliptin	VE009114	View
Oxo Sitagliptin	VE008998	View
Oxo-N-Boc Sitagliptin	VE009003	View
Sitagliptin 1, 2, 4-Trifluorobenzene	VE006177	View CAS 367-23-7
Sitagliptin 2 4 Difluorophenylaetic acid	VL201004	View CAS 81228-09-3
Sitagliptin 2 5 difluoro phenyl acetic acid	VL201003	View CAS 85068-27-5
Sitagliptin 2, 3, 6-Trifluorophenylacetic acid	VE006178	View CAS 114152-23-7
Sitagliptin 2-Chloro Hydrazide Impurity	VL201026	View
Sitagliptin 2-Desfluoro Impurity	VE009000	View CAS 486459-88-5
Sitagliptin 3-4 Difluorophenyl Acetic Acid	VL201002	View CAS 658-93-5
Sitagliptin Acid Impurity	VL201013	View CAS 1204818-19-8
Sitagliptin BOC Butanoic Acid	VL201036	View
Sitagliptin Dimer Impurity	VL201028	View CAS 2072867-07-1
Sitagliptin Dioxo Impurity	VL201016	View
Sitagliptin Dioxo Impurity (Sodium Salt)	VE006424	View
Sitagliptin EP Impurity A	VE006598	View CAS 823817-55-6
Sitagliptin EP Impurity A (HCl salt)	VL201001	View
Sitagliptin EP Impurity A (Phosphate Salt)	VE006482	View CAS (823817-58-9)
Sitagliptin EP Impurity B	VL201006	View CAS 1345822-87-8
Sitagliptin EP Impurity B (Phosphate Salt)	VL201032	View
Sitagliptin EP Impurity C	VL201005	View CAS 1345822-86-7
Sitagliptin EP Impurity C (Phosphate Salt)	VL201031	View
Sitagliptin Enamine Impurity	VL201014	View CAS 767340-03-4
Sitagliptin Fumarate Adduct	VL201021	View CAS 2088771-60-0
Sitagliptin Hydroxy Amide Impurity	VE008997	View CAS 1253056-01-7
Sitagliptin Imidazole Derivative	VE008964	View CAS 1364122-90-6
Sitagliptin Impurity 1	VL201008	View
Sitagliptin Impurity 4	VL201011	View CAS 486460-23-5
Sitagliptin Impurity F (In House)	VL201022	View
Sitagliptin Keto Amide Impurity	VL201015	View CAS 764667-65-4
Sitagliptin N-Acetyl Impurity	VE008598	View CAS 1379666-94-0
Sitagliptin N-Formyl Impurity	VE006565	View
Sitagliptin Phenyl Crotonyl Analog	VL201025	View CAS 1253056-18-6
Sitagliptin Pyrazinone Impurity	VE009001	View CAS 877402-45-4
Sitagliptin Styrylacetyl Analog	VL201024	View CAS 1803026-58-5
Sitagliptin Tartrate Hemihydrate	VL201020	View
Sitagliptin Triazecine Analog	VL201018	View CAS 2088771-61-1
Sitagliptin Triazole Impurity	VL201012	View
Tert-Butyl 3-(Trifluoromethyl)-5, 6-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazine-7(8H)-carboxylate	VE009004	View CAS 877402-43-2
Tert-Butyl 8-Oxo-3-(trifluoromethyl)-5, 6-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazine-7(8H)-carboxylate	VE009006	View CAS 877402-44-3
2, 3, 4-Trifluorophenylacetic Acid	VE008129	View CAS 243666-12-8
2, 3, 5-Trifluorophenylacetic Acid	VE008130	View CAS 132992-28-0
2, 4, 5-Trifluorobenzyl chloride	VE006099	View CAS 243139-71-1
2, 4, 6-Trifluorophenylacetic Acid	VE008131	View CAS 209991-63-9
2-desfluoro N-Boc methyl ester Impurity	VE008999	View
3-Hydroxy-3, 4-Dicaboxy-Butanamide-N-Hexanoic Acid	VL201023	View
5-(2-(2, 5-difluorophenyl)-1-hydroxyethylidene)-2, 2-dimethyl-1, 3-dioxane-4, 6-dione	VE009007	View CAS 764667-66-5
5-(Trifluoromethyl)-2-(chloromethyl)-1, 3, 4-oxadiazole	VE0010888	View CAS 723286-98-4
(2Z)-1-[5, 6-Dihydro-3-(trifluoromethyl)-1, 2, 4-triazolo[4, 3-a]pyrazin-7(8H)-yl]-4-(2, 4, 5-trifluorophenyl)-2-buten-1-one	VE008780	View CAS 1803026-54-1
(3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2, 4-difluorophenyl)butanoic Acid	VE009008	View CAS 851307-12-5
(E)-1-(3-(trifluoromethyl)-5, 6-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazin-7(8H)-yl)-4-(2, 4, 5-trifluorophenyl)but-2-en-1-one	VE009354	View
(R)-Sitagliptin Methyl-Ester Impurity	VL201034	View CAS 881995-69-3
(R)-Sitagliptin Methyl-Ester Impurity (HCl Salt)	VE008550	View CAS 1374985-05-3
(R)-Sitagliptin N-Boc-Methyl-Ester Impurity	VE006048	View CAS 881995-73-9
(S)-Sitagliptin N-Boc-Acid Impurity	VL201030	View CAS 922178-94-7
(Z)-2, 2, 2-trifluoro-N'-(piperazin-2-ylidene)acetohydrazide	VE0010889	View CAS 763105-70-0

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