(4S)-2-{[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido](carboxy)methyl}-5,5-dimethylthiazolidine-4-carboxylic acid monosodium salt
同義語
Amoxicillin Related compound D sodium salt; Amoxicillin Penicilloic Acid Sodium Salt
説明
Amoxicillin Related compound D sodium salt, CAS 1642559-71-4 は、ペナム骨格に由来する既知の工程由来不純物であり、β-ラクタム系抗生物質の製造および安定性に関連する。分子式 C16H20NaN3O6S、分子量 405.40 g/mol を有し、単なる賦形剤残留ではなく、アモキシシリン関連化合物のナトリウムカルボキシラート体として位置づけられる。生成機構としては、アシル側鎖の転位、加水分解変換、または合成中間体の持ち越しが想定される。同定と定量には、LC-MS/MS、LC-HRMS、ならびに補完的な HPLC-UV が一般に必要であり、薬局方および ICH に基づく不純物管理の文脈で評価される。
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