Abacavir EP Impurity F
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データの正確性100%
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内容: HPLC、MASS/LC-MS、1H NMR、FT-IR、含量、構造解析レポート(SER)、および製品に応じた追加分析データ。

1443421-68-8Abacavir EP Impurity F

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カタログ番号:VL760003
CAS番号:1443421-68-8
分子式:C18H26N6O
分子量:342.44 g/mol

に関する追加情報 CAS 1443421-68-8

親薬物

Abacavir

IUPAC名

6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine

薬局方同義語

T-Butyl Derivative Abacavir

Other Synonyms

O-t-Butyl Derivative Abacavir; Abacavir t-Butyl Ether; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine; N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine; 6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine; 9-[(1R,4S)-4-(tert-butoxymethyl)cyclopent-2-en-1-yl]-N6-cyclopropylpurine-2,6-diamine

説明

Abacavir EP Impurity F(CAS No: 1443421-68-8) or T-Butyl Derivative Abacavir is an impurity formed by the degradation of Abacavir that is a nucleoside reverse transcriptase inhibitor utilized in the treatment of human immunodeficiency virus infection, and mainly helps to obstruct the inroads of the human immunodeficiency virus.

References

Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.

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