1443421-68-8: Abacavir EP Impurity F

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Abacavir EP Impurity F(CAS No: 1443421-68-8) or T-Butyl Derivative Abacavir is an impurity formed by the degradation of Abacavir that is a nucleoside reverse transcriptase inhibitor utilized in the treatment of human immunodeficiency virus infection, and mainly helps to obstruct the inroads of the human immunodeficiency virus.

Additional information on CAS 1443421-68-8

Catalogue No. VL760003
CAS No. 1443421-68-8
Molecular Formula C18H26N6O
Molecular Weight 342.44 g/mol
Parent drug Abacavir
IUPAC Name 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine
Pharmacopoeial Synonyms T-Butyl Derivative Abacavir
Other Synonyms O-t-Butyl Derivative Abacavir; Abacavir t-Butyl Ether; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine; N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine; 6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine; 9-[(1R,4S)-4-(tert-butoxymethyl)cyclopent-2-en-1-yl]-N6-cyclopropylpurine-2,6-diamine
References Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.
Status In-stock

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