Stock Locations

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Stock subject to availability.

Documentation

Download MSDS

Download Sample COA

Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

1443421-68-8Abacavir EP Impurity F

● In Stock

Catalogue No.:	VL760003
CAS No.:	1443421-68-8
Mol. Formula:	C18H26N6O
Mol. Weight:	342.44 g/mol

Request a quote

Add to RFQ list

Additional information on CAS 1443421-68-8

Parent drug

Abacavir

IUPAC Name

6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine

Pharmacopoeial Synonyms

T-Butyl Derivative Abacavir

Other Synonyms

O-t-Butyl Derivative Abacavir; Abacavir t-Butyl Ether; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine; N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine; 6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine; 9-[(1R,4S)-4-(tert-butoxymethyl)cyclopent-2-en-1-yl]-N6-cyclopropylpurine-2,6-diamine

Description

Abacavir EP Impurity F(CAS No: 1443421-68-8) or T-Butyl Derivative Abacavir is an impurity formed by the degradation of Abacavir that is a nucleoside reverse transcriptase inhibitor utilized in the treatment of human immunodeficiency virus infection, and mainly helps to obstruct the inroads of the human immunodeficiency virus.

References

Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.