Cabozantinib Carboxylic Acid, CAS 849217-77-2, é uma impureza definida de natureza oxidativa e hidrolítica associada ao cabozantinib, formada por oxidação da cadeia lateral ou clivagem da ligação amida durante a síntese, o armazenamento ou condições de estresse. Com fórmula molecular C22H20N2O6 e massa molecular de 408.4 g/mol, trata-se de um degradante polar e não volátil, não de uma nitrosamina nem de outro alerta estrutural genotóxico direto. Sua detecção e quantificação geralmente requerem LC-MS/MS, LC-MS de alta resolução e HPLC indicativa de estabilidade com detecção por UV ou arranjo de diodos, com apoio de RMN para confirmação estrutural. No perfil de impurezas, funciona como marcador de degradação molecular e robustez do processo.
Solicitar orçamento
"*" indica campos obrigatórios
Outros produtos relacionados às Cabozantinib impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
