Eltrombopag Impurity 15 (CAS 376592-58-4) é uma substância relacionada definida do agonista do receptor de trombopoetina de pequena molécula eltrombopague, com fórmula molecular C13H8ClNO5 e massa molecular de 293,66 g/mol. A sua estrutura é compatível com um impureza aromática clorada e altamente oxigenada, proveniente de degradação ou intermediário de síntese, e não com uma simples forma salina. Espécies desse tipo são monitoradas pela formação sob estresse oxidativo e pelo comportamento cromatográfico distinto. A detecção e a quantificação normalmente exigem LC-MS/MS, LC-MS de alta resolução e métodos ortogonais de HPLC-UV no perfil de impurezas.
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