?-2-7-Aminodesacetoxycephalosporanic Acid (CAS 56487-68-4) es una impureza crítica del núcleo cefalosporánico que puede formarse durante etapas de desprotección y modificación en procesos sintéticos | generando pérdida del grupo acetoxi y la aparición de un amino en posiciones clave que altera polaridad y comportamiento cromatográfico; su presencia impacta la pureza y estabilidad del lote. La identificación y cuantificación requieren HPLC con detección UV | LC-MS para confirmación de masa y RMN para asignación estructural. El control riguroso incluye límites de especificación | estudios de degradación forzada y métodos analíticos validados para mitigar riesgos de calidad.
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