Metoprolol EP Impurity A (CAS 109632-08-8) | también denominada Metoprolol Related Compound A | Metoprolol Succinate EP Impurity A | C-Desmethyl Metoprolol | N-Desisopropyl-N-ethylmetoprolol o 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol | es una impureza identificada en el control de calidad de lotes de metoprolol; su perfil analítico incluye espectros compatibles por LC-MS | HPLC y RMN que permiten su cuantificación y confirmación estructural. La presencia de esta impureza puede influir en especificaciones de pureza y estabilidad | por lo que se recomienda establecer límites de aceptación | métodos validados de detección y estudios de degradación forzados para garantizar cumplimiento con monografías farmacopéuticas.
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