Telmisartan-Dibromo impureza (CAS 1352492-08-0) es un subproducto halogenado observado en síntesis y degradación de telmisartán. Su perfil químico muestra incorporación de dos átomos de bromo en el núcleo aromático | lo que altera polaridad y masa molecular y afecta parámetros de purificación y cromatografía. La caracterización analítica requiere HPLC con detector UV | espectrometría de masas y RMN para confirmar patrón isotópico y posición de sustitución. Su monitorización es crítica para el control de calidad y cumplimiento de especificaciones de impurezas | evaluación de estabilidad y optimización de procesos para minimizar formación durante síntesis y almacenamiento.
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