Telmisartan EP Impurity I, CAS 528560-93-2, es el análogo metil éster del ácido telmisartán, descrito formalmente como metil 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoato, con fórmula molecular C34H32N4O2 y peso molecular 528.64 g/mol. Suele originarse por hidrólisis incompleta del éster o por transesterificación durante la síntesis o el almacenamiento de intermedios de telmisartán. Como impureza estructural de proceso, y no como entidad genotóxica específica, su control se basa en el perfilado de impurezas y el establecimiento de límites. La detección y cuantificación suelen requerir LC-MS/MS o LC-UV con confirmación por espectrometría de masas.
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