4-Butyrylamino-3-methyl-5-nitrobenzoic Acid Methyl Ester (CAS 152628-01-8) es una impureza orgánica relevante en procesos sintéticos que involucran acilación y esterificación. Presenta características físicoquímicas: baja solubilidad en agua | mayor polaridad relativa por el grupo nitro y amida | y susceptibilidad a reducción y transesterificación. Su formación suele originarse por reacciones secundarias durante la metilación o por contaminantes en el reactivo. Se detecta y cuantifica con métodos analíticos como HPLC con detección UV y LC-MS para perfilar y controlar el límite de aceptación. Su presencia afecta pureza | estabilidad y rendimiento del lote por lo que requiere monitoreo | almacenamiento anhidro y límites de especificación estrictos.
Referencias
Gosse, Philippe. “A Review of Telmisartan in the Treatment of Hypertension: Blood Pressure Control in the Early Morning Hours.†Vascular Health and Risk Management, vol. 2, no. 3, Aug. 2006, pp. 195–201, https://doi.org/10.2147/vhrm.2006.2.3.195. ‌
Solicitar cotización
"*" señala los campos obligatorios
Otros productos relacionados con Telmisartan impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Siempre activo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Siempre activo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
![4'-(((2-aminophenyl)amino)methyl)-[1,1'-biphenyl]-3-carboxylic acid](https://veeprho.com/wp-content/uploads/2023/06/4-2-aminophenyl-amino-methyl-1-1-biphenyl-3-carboxylic-acid.png "4'-(((2-aminophenyl)amino)methyl)-[1,1'-biphenyl]-3-carboxylic acid")
![N,N'-(1,2-phenylene)bis(4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxamide)](https://veeprho.com/wp-content/uploads/2023/06/N-N-1-2-phenylene-bis-4-methyl-2-propyl-1H-benzo-d-imidazole-6-carboxamide.png "N,N'-(1,2-phenylene)bis(4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxamide)")
