Abiraterone Acetate N-Oxide

Status: Under Development

Abiraterone Acetate N-Oxide is an impurity of Abiraterone acetate that is a prodrug used in castration-resistant prostate cancer by getting converted in vivo to abiraterone that acts by an androgen biosynthesis inhibition. It affects cancerous tissue as well as the natural synthesis of androgens.

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Additional information on Abiraterone Acetate N-Oxide

Catalogue No. VL830049
Molecular Formula C26H33NO3
Molecular Weight 407.55
Parent drug Abiraterone
IUPAC Name 3-((3S, 8R, 9S, 10R, 13S, 14S)-3-acetoxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxide
Synonyms N/A
References Mach, Samuel, et al. “Epoxidation Is the Preferred Pathway of First-Stage Metabolism of Abiraterone Acetate in Brown Bullhead (Ameiurus Nebulosus).” Environmental Science and Pollution Research, vol. 26, no. 34, Oct. 2019, pp. 34896–904, https://doi.org/10.1007/s11356-019-06568-y. ?
Status Under Development

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