100% accuracy
of data
of data
24/7 scientific
support
support
0% tolerance in
quality of product
quality of product
Stock Locations
- New Jersey, USA
- Czech Republic, EU
- Mumbai, India
* Stock subject to availability.
Documentation
Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.
2517964-85-9Abiraterone Acetate N-Oxide
● Under Development
| Catalogue No.: | VL830049 |
|---|---|
| CAS No.: | 2517964-85-9 |
| Mol. Formula: | C26H33NO3 |
| Mol. Weight: | 407.55 g/mol |
Additional information on CAS 2517964-85-9
Parent drug
AbirateroneIUPAC Name
3-((3S, 8R, 9S, 10R, 13S, 14S)-3-acetoxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxidePharmacopoeial Synonyms
N/AOther Synonyms
17-(Pyridin-3-yl)androsta-5,16-dien-3β-yl Acetate N-oxideSmiles
C[C@@]12C(C3=C[N+]([O-])=CC=C3)=CC[C@@]1([H])[C@]4([H])CC=C5C[C@@H](OC(C)=O)CC[C@]5(C)[C@@]4([H])CC2InChI
InChI=1S/C26H33NO3/c1-17(28)30-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27(29)16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21-,23-,24-,25-,26+/m0/s1Description
Abiraterone Acetate N-Oxide is an impurity of Abiraterone acetate that is a prodrug used in castration-resistant prostate cancer by getting converted in vivo to abiraterone that acts by an androgen biosynthesis inhibition. It affects cancerous tissue as well as the natural synthesis of androgens.
References
Mach, Samuel, et al. “Epoxidation Is the Preferred Pathway of First-Stage Metabolism of Abiraterone Acetate in Brown Bullhead (Ameiurus Nebulosus).†Environmental Science and Pollution Research, vol. 26, no. 34, Oct. 2019, pp. 34896–904, https://doi.org/10.1007/s11356-019-06568-y. ?Request a Quote
"*" indicates required fields
Other products related to Abiraterone impurities
Impurity structure
Parent Drug Name
CAS No.
Name of Impurity
Catalog No.
