138768-62-4: N-Nitroso Metoprolol

N-Nitroso Metoprolol (CAS No: 138768-62-4) is the impurity present in metoprolol that has been shown to decrease cardiovascular disease risk in patients with hypertension and type 2 diabetes mellitus and is advantageous in idiopathic dilated cardiomyopathy.

Additional information

Catalogue No.

VE007073

CAS No.

138768-62-4

Molecular Formula

C15H24N2O4

Molecular Weight

296.36 g/mol

IUPAC Name

N-(2-hydroxy-3-(4-(2-methoxyethyl)phenoxy)propyl)-N-isopropylnitrous amide

References

Seshadri, Raja Kumar. “Simultaneous Quantitative Determination of Metoprolol, Atorvastatin and Ramipril in Capsules by a Validated Stability-Indicating RP-UPLC Method.” Scientia Pharmaceutica, vol. 78, no. 4, 2010, pp. 821–34, https://doi.org/10.3797/scipharm.1004-14. Bakris, George L., et al. “Metabolic Effects of Carvedilol vs Metoprolol in Patients with Type 2 Diabetes Mellitus and Hypertension.” JAMA, vol. 292, no. 18, Nov. 2004, p. 2227, https://doi.org/10.1001/jama.292.18.2227.

Status

In-stock