3 Hydroxy Abacavir

Status: Under Development

3 Hydroxy Abacavir is formed by degradation of Abacavir is a purine analog and an antiretroviral drug that acts by decreasing viral load and increasing CD4+ cell count for the treatment of human immunodeficiency virus infection.

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Additional information on 3 Hydroxy Abacavir

Catalogue No. VL760008
CAS No. N/A
Molecular Formula C14H20N6O2
Molecular Weight 304.35
Parent drug Abacavir
IUPAC Name (1R, 2R, 4S)-2-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-4-(hydroxymethyl)cyclopentanol
Synonyms N/A
References Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. Foster RH, Faulds D. Abacavir. Drugs. 1998 May;55(5):729-36; discussion 737-8. DOI: 10.2165/00003495-199855050-00018. PMID: 9585869.
Status Under Development

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