1443421-69-9: Abacavir EP Impurity B

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Abacavir EP Impurity B (CAS No: 1443421-69-9) or Abacavir O-Pyrimidine Impurity / Abacavir Related Compound D is synthesized by degradation of Abacavir which is a nucleoside reverse transcriptase inhibitor and Its mechanism include chain termination subsequent to incorporation into the growing polynucleotide strand. It is used in the treatment of HIV infection.

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Additional information on CAS 1443421-69-9

Catalogue No. VL760001
CAS No. 1443421-69-9
Molecular Formula C18H21ClN10O
Molecular Weight 428.8
Parent drug Abacavir
IUPAC Name 6-(Cyclopropylamino)-9-[(1R, 4S)-4-[[(2, 5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine
Synonyms Abacavir O-Pyrimidine Impurity / Abacavir Related Compound D
References Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. ?Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination
Status In-stock

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1443421-69-9: Abacavir EP Impurity B

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