172015-79-1: Abacavir Related Compound C

Status: Under Development

Abacavir Related Compound C (CAS No: 172015-79-1) or Abacavir 6-Chloro Analog is an analog of Abacavir that is the first member of the carbocyclic nucleosides family to be recommended for use for HIV. Thus having anti-HIV activity comparable to that of carbolic against HIV-1 in MT-4 cells.

Additional information on CAS 172015-79-1

Catalogue No. VL760026
CAS No. 172015-79-1
Molecular Formula C11H13Cl2N5O
Molecular Weight 302.16 g/mol
Parent drug Abacavir
IUPAC Name (1S, 4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride
Pharmacopoeial Synonyms N/A
Other Synonyms ABACAVIR CHLOROPURINE DERIVATIVE; ((1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hydrochloride; (1S-4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride; [(1S,4R)-4-(2-amino-6-chloropurin-9-yl)cyclopent-2-en-1-yl]methanol;hydrochloride; (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol HCl; [(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)cyclopent-2-enyl]methanol Hydrochloride; [(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol–hydrogen chloride (1/1)
References ?Canoa, Pilar, et al. “Synthesis and Anti-HIV Activity of Novel Cyclopentenyl Nucleoside Analogues of 8-Azapurine.” Chemical and Pharmaceutical Bulletin, vol. 54, no. 10, 2006, pp. 1418–20, https://doi.org/10.1248/cpb.54.1418. ?
Status Under Development

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