267668-71-3: Abacavir EP Impurity D (HCl Salt)

Status: In-stock

Also known as Abacavir Related Compound 8 or trans-Abacavir Dihydrochloride, it is formed by the degradation of Abacavir. Abacavir is an antiretroviral drug that acts by decreasing viral load and increasing CD4+ cell count in HIV-infected patients.

Additional information on CAS 267668-71-3

Catalogue No. VL760005
CAS No. 267668-71-3
Molecular Formula C14H20Cl2N6O
Molecular Weight 359.25 g/mol
Parent drug Abacavir
IUPAC Name (1R, 4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol dihydrochloride
Pharmacopoeial Synonyms trans Abacavir
Other Synonyms {(1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol–hydrogen chloride (1/2); Rel-((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol dihydrochloride; [(1R,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol dihydrochloride
References Foster RH, Faulds D. Abacavir. Drugs. 1998 May;55(5):729-36; discussion 737-8. DOI: 10.2165/00003495-199855050-00018. PMID: 9585869. Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019.
Status In-stock

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267668-71-3: Abacavir EP Impurity D (HCl Salt)

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