384380-52-3: Abacavir Carboxylate

Status: Under Development

Abacavir Carboxylate (CAS No: 384380-52-3) is a metabolite of Abacavir that is a nucleoside analog having HIV-1 reverse transcriptase inhibition property and a potent in vivo and in vitro inhibition property of HIV-1 that leads to acquired immunodeficiency syndrome.

Additional information on CAS 384380-52-3

Catalogue No. VL760021
CAS No. 384380-52-3
Molecular Formula C14H16N6O2
Molecular Weight 300.32 g/mol
Parent drug Abacavir
IUPAC Name (1S, 4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid
Pharmacopoeial Synonyms N/A
Other Synonyms Abacavir 5'-carboxylate; 5'-oxoabacavir; Abacavir carboxylic acid; Abacavir 5'-carboxylic acid; (1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-ene-1-carboxylic acid; 2-Cyclopentene-1-carboxylic acid; carboxy-abacavir; 2-Cyclopentene-1-carboxylic acid, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic acid
References Ravitch, Joshua R., and Caroline G. Moseley. “High-Performance Liquid Chromatographic Assay for Abacavir and Its Two Major Metabolites in Human Urine and Cerebrospinal Fluid.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 762, no. 2, Oct. 2001, pp. 165–73, https://doi.org/10.1016/s0378-4347(01)00361-9.
Status Under Development

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384380-52-3: Abacavir Carboxylate

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