N-nitroso-N-desmethylnintedanib

N-nitroso-N-desmethylnintedanib or methyl (Z)-3-(((4-(N-methyl-2-(4-nitrosopiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, is a triple angiokinase inhibitor, is a small molecule, competitive that used for the treatment of idiopathic pulmonary fibrosis, interstitial lung disease. it acts to inhibit platelet-derived growth factors and fibroblast growth factor receptors.

Additional information

Catalogue No.

VE009403

CAS No.

N/A

Molecular Formula

C30H30N6O5

Molecular Weight

554.60 g/mol

IUPAC Name

methyl (Z)-3-(((4-(N-methyl-2-(4-nitrosopiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

References

Rivera-Ortega, Pilar, et al. “Nintedanib in the Management of Idiopathic Pulmonary Fibrosis: Clinical Trial Evidence and Real-World Experience.” Therapeutic Advances in Respiratory Disease, vol. 12, Jan. 2018, p. 175346661880061, https://doi.org/10.1177/1753466618800618. ‌

Status

In-stock