Nintedanib Nitroso Impurity 1

Nintedanib Nitroso Impurity 1 or methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6carboxylate, is a triple angiokinase inhibitor, is a small molecule, competitive that used for the treatment of idiopathic pulmonary fibrosis, interstitial lung disease. it acts to inhibit platelet-derived growth factors and fibroblast growth factor receptors.

Additional information

Catalogue No.

VE009401

CAS No.

N/A

Molecular Formula

C31H32N6O5

Molecular Weight

568.6 g/mol

IUPAC Name

methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6carboxylate

References

Liu, Feng, et al. “Application of Nintedanib and Other Potential Anti-Fibrotic Agents in Fibrotic Diseases.” Clinical Science, vol. 133, no. 12, June 2019, pp. 1309–20, https://doi.org/10.1042/cs20190249. ‌

Status

In-stock