Nintedanib Nitroso Impurity 1
Nintedanib Nitroso Impurity 1 or methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6carboxylate, is a triple angiokinase inhibitor, is a small molecule, competitive that used for the treatment of idiopathic pulmonary fibrosis, interstitial lung disease. it acts to inhibit platelet-derived growth factors and fibroblast growth factor receptors.
Additional information on Nintedanib Nitroso Impurity 1
VE009401
N/A
C31H32N6O5
568.6 g/mol
Nintedanib
methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6carboxylate
N/A
Liu, Feng, et al. “Application of Nintedanib and Other Potential Anti-Fibrotic Agents in Fibrotic Diseases.” Clinical Science, vol. 133, no. 12, June 2019, pp. 1309–20, https://doi.org/10.1042/cs20190249.
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